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Powder Characterization Using FT4 Powder Rheometry

At Seven Star Pharmaceutical Services, our FT4 Powder Rheometer allows us to provide comprehensive powder flow characterization, essential in various stages of pharmaceutical development, particularly in formulation and manufacturing. Understanding powder flow properties plays a critical role in optimizing processes such as mixing, granulation, and tableting, ensuring consistent product quality and performance.

Key Capabilities of the FT4 Powder Rheometer

The FT4 Powder Rheometer is a versatile and advanced instrument designed to measure a wide range of powder properties. It provides insights into dynamic, bulk, and shear properties, critical for determining how powders behave under different conditions. The instrument’s unique capabilities include:
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  • Dynamic Flow Properties:  Measures parameters such as basic flowability energy, specific energy, and flow rate index to assess how powders behave in motion, which is particularly useful for processes involving transportation and dosing.

  • Bulk Properties: Evaluates density, compressibility, and permeability, key indicators of powder stability and compaction behavior. These measurements help understand packing behavior and optimize formulations for consistent dosing.

  • Shear Properties: Assesses parameters like cohesion and wall friction to analyze powder flow under stress, ensuring smooth processing during manufacturing and reducing operational risks.

FT4_Powder_Rheometer at Seven Star

FT4 Powder Rheometer (at Seven Star)

Applications in Pharmaceutical Development

Our FT4 Powder Rheometer services support various aspects of pharmaceutical development, including:​​

  • Preformulation Studies:  Identifying optimal powder characteristics for blending, granulation, and tableting, essential for achieving desired consistency and bioavailability.

  • Formulation Development: Enhancing formulation robustness by understanding powder properties that affect mixing, tablet compression, and capsule filling.

  • Process Optimization: Providing insights into factors influencing manufacturing efficiency, such as flowability and compressibility, contributing to cost-effective and high-quality production.

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